Short Name | Description | Coordinating Institution |
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Genetic regulation of protein glycosylation | To identify gene network that regulate IgG and plasma protein glycosylation by performing genome wide association studies | Genos Glycoscience Research Laboratory (Gordan Lauc, glauc_at_genos.hr) |
Glycomic signatures of human diseases | To determine changes in the glycome that associate with major human diseases | Leiden University Medical Centre (Manfred Wuhrer, m.wuhrer_at_lumc.nl) |
Cancer glycomics | Determining the glycosylation signatures of human cancers | Institute for Glycomics, Griffith University (Daniel Kolarich, d.kolarich_at_griffith.edu.au) |
Host glycomic signature of HIV infection | Investigating the role of host glycosylation machinery in HIV persistence and immunopathogenesis | The Wistar Institute (Mohamed Abdel-Mohsen, mmohsen_at_wistar.org) |
Total plasma and IgG glycomes, statin therapy, and ASCVD events | To determine predictive power of total plasma and IgG glycome for atherosclerotic cardiovascular disease | Harvard Medical School (Samia Mora, smora_at_bwh.harvard.edu) |
Glycomics and glycoproteomics in liver disease | To analyse tissue and biofluid glycans and glycopeptides as biomarkers of liver disease | Medical University of South Carolina (Anand Mehta, mehtaa_at_musc.edu) |
Urine glycomics and glycoproteomics | To analyse tissue and biofluid glycans and glycopeptides as biomarkers of prostate disease | Medical University of South Carolina (Richard Drake, draker_at_musc.edu) |
Plasma, tissue, urine and gut bacteria glycome in cancer, neuron, and diabetes | To characterize N-glycan, O-glycan and proteoglycan in serum, urine and intestinal bacteria glycome in individuals | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (Kan Ding, dingkan_at_simm.ac.cn) |
Host glycosylation during bacterial infection | Deciphering the role of mononuclear phagocyte glycans in response to bacterial infection | Institute of Pharmacology and Structural Biology, CNRS-Toulouse University (Yoann Rombouts, yoann.rombouts_at_ipbs.fr) |
Cell specific glycomics and glycoproteomics in autoimmunity and cancer | To characterise in a tissue and cell-specific manner (immune and non-immune cells) the glycans signature and its functional relevance in cancer and autoimmunity. | Institute of Molecular Pathology and Immunology of University of Porto (Salomé Pinho, salomep_at_ipatimup.pt) |
Functional glycomics and glycoproteomics in cancer | To determine glycans functional modulation in cancer biology and therapy response. | Institute of Molecular Pathology and Immunology of the University of Porto (Celso Reis, celsor_at_ipatimup.pt) |
The uromoduline glycome | Staging uromoduline glycosylation in controls and patients suffering from urogenital infections and kidney stones | Hannover Medical School (Rita Gerardy-Schahn, Gerardy-Schahn.Rita_at_mh-hannover.de) |
Human milk oligosaccharide (HMO) biosynthesis and function | To study the biosynthetic pathway as well as structure function relationship of human milk oligosaccharides for infant health and development and throughout the lifecycle | UC San Diego Larsson- Rosenquist Foundation Mother- Milk-Infant Center of Research Excellence (Lars Bode) |
Human milk oligosaccharide (HMO) biosynthesis and function | To study the biosynthetic pathway as well as structure function relationship of human milk oligosaccharides for infant health and development and throughout the lifecycle | UC San Diego Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (Lars Bode) |
Epigenetic regulation of the IgG glycome | To study epigenetic mechanisms that contribute to regulation of IgG glycosylation | University of Zagreb Faculty of Science (Vlatka Zoldoš) |
Lung cancer vs COPD | Comparative large clinical N-glycomic study of 1200 lung cancer (LC), COPD, and LC+COPD patients | HLBS, University of Debrecen, Hungary (Andras Guttman) |